Joshua J. Joseph, MD, MPH, FAHA
Dr. Joseph’s research focus is to understand risk factors for the development of obesity and type 2 diabetes in diverse populations. His group examines the role of the renin-angiotensin-aldosterone system and the hypothalamic-pituitary-adrenal axis, specifically aldosterone and cortisol, in the development of diabetes and obesity using data from longitudinal observational cohorts. He has also been working to shed light on racial and ethnic differences in the association of physical activity and other lifestyle factors in the development of diabetes using large multi-ethnic observational cohorts including the Multi-Ethnic Study of Atherosclerosis (MESA) and the Jackson Heart Study. The hypotheses generated using epidemiological approaches is used to design and execute detailed metabolic clinical studies to uncover explanatory mechanisms as potential targets for preventive interventions for diabetes and obesity.